• Corpus ID: 5106622

Change in sleep Temperamental traits Substance use Misuse and dependence Antidepressant use Environmental factors Abuse and maltreatment Conflictual family

  title={Change in sleep Temperamental traits Substance use Misuse and dependence Antidepressant use Environmental factors Abuse and maltreatment Conflictual family},
  author={Xavier Benarous and Ang{\`e}le Consoli and Vanessa Milhiet and David Cohen},
developing BD should include repeated measures of putative biomarkers. Staging models have been developed as an integrative approach to specify the individual level of risk based on clinical (e.g. prodromal symptoms and familial history of BD) and non-clinical (e.g. biomarkers and neuroimaging) data. However, there is still a lack of empirically validated studies that measure the benefits of using these models to design preventive intervention programmes. 

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