Change in membrane fluidity induced by lectin-mediated phase separation of the membrane and agglutination of phospholipid vesicles containing glycopeptides.

@article{Ohtoyo1988ChangeIM,
  title={Change in membrane fluidity induced by lectin-mediated phase separation of the membrane and agglutination of phospholipid vesicles containing glycopeptides.},
  author={Takehiko Ohtoyo and Masayuki Shimagaki and Kazuya Otoda and Shunsaku Kimura and Yukio Imanishi},
  journal={Biochemistry},
  year={1988},
  volume={27 17},
  pages={
          6458-63
        }
}
Changes in membrane fluidity induced by lectin addition to 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) vesicles containing synthetic glycopeptides were measured by depolarization of the fluorescent probes 8-anilino-1-naphthalenesulfonate (ANS) and 1,6-diphenyl-1,3,5-hexatriene (DPH). In the present synthesized glycopeptides, N-acetylglucosamine (GlcNAc) and a tripeptide were connected by aliphatic chains of different lengths. A pyrenyl group, which is introduced to the peptide moiety… Expand
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