Change in hippocampal volume on magnetic resonance imaging and cognitive decline among older depressed and nondepressed subjects in the neurocognitive outcomes of depression in the elderly study.

@article{Steffens2011ChangeIH,
  title={Change in hippocampal volume on magnetic resonance imaging and cognitive decline among older depressed and nondepressed subjects in the neurocognitive outcomes of depression in the elderly study.},
  author={David C. Steffens and Douglas R. McQuoid and Martha E. Payne and Guy G. Potter},
  journal={The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year={2011},
  volume={19 1},
  pages={
          4-12
        }
}
INTRODUCTION previous studies have linked hippocampal volume change and cognitive decline in older adults with dementia. The authors examined hippocampal volume change and cognitive change in older nondemented adults with and without major depression. METHODS the sample consisted of 90 depressed individuals and 72 healthy, nondepressed individuals aged 60 years and older who completed at least 2 years of follow-up data. All patients underwent periodic clinical evaluation by a geriatric… CONTINUE READING
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