Change in hepatic handling of hepatocyte growth factor during liver regeneration in rats.

@article{Liu1995ChangeIH,
  title={Change in hepatic handling of hepatocyte growth factor during liver regeneration in rats.},
  author={Kexin Liu and Yutaro Kato and Tetsuya Terasaki and Toshifumi Nakamura and Yuichi Sugiyama},
  journal={The American journal of physiology},
  year={1995},
  volume={269 5 Pt 1},
  pages={G745-53}
}
The change in the hepatic uptake clearance of hepatocyte growth factor (HGF) during liver regeneration in rats was examined. The hepatic uptake clearance per gram liver of 125I-labeled HGF in vivo decreased to a minimum level only 15 min after partial hepatectomy (PH). In the perfused liver, in which the effect of endogenous substances can be ignored, the hepatic uptake clearance of 125I-HGF did not change until at least 3 h after PH, suggesting that the decrease in the clearance in vivo is… CONTINUE READING