Change in estimated GFR associates with coronary heart disease and mortality.

  title={Change in estimated GFR associates with coronary heart disease and mortality.},
  author={Kunihiro Matsushita and Elizabeth Selvin and Lori D. Bash and Nora Franceschini and Brad C Astor and Josef Coresh},
  journal={Journal of the American Society of Nephrology : JASN},
  volume={20 12},
Kidney function predicts cardiovascular and all-cause mortality, but little is known about the association of changes in estimated GFR (eGFR) with clinical outcomes. We investigated whether 3- and 9-yr changes in eGFR associated with risk for coronary heart disease (CHD) and all-cause mortality among 13,029 participants of the Atherosclerosis Risk in Communities (ARIC) Study. After adjustment for baseline covariates including eGFR in Cox proportional hazards models, the quartile of participants… CONTINUE READING
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