Change in creatinine clearance over time following upper abdominal irradiation: a dose-volume histogram multivariate analysis.

@article{Diavolitsis2011ChangeIC,
  title={Change in creatinine clearance over time following upper abdominal irradiation: a dose-volume histogram multivariate analysis.},
  author={Virginia M Diavolitsis and Alfred Rademaker and John W Boyle and Zhuang Kang and Krystyna Kiel and Mary Frances Mulcahy and William Small},
  journal={American journal of clinical oncology},
  year={2011},
  volume={34 1},
  pages={53-7}
}
OBJECTIVES To investigate the change in creatinine clearance (CrCl) over time following upper abdominal radiation utilizing a dose-volume histogram (DVH) multivariate analysis. METHODS The study population included 125 patients with gastrointestinal malignancy treated with abdominal radiation therapy at our institution between 1994 and 2006, with available creatinine and DVH information. Kidney dose-volume data collected included mean kidney dose, volume of kidney irradiated, V5, V10, and V20… CONTINUE READING