Change in brain network connectivity during PACAP38-induced migraine attacks: A resting-state functional MRI study.

@article{Amin2016ChangeIB,
  title={Change in brain network connectivity during PACAP38-induced migraine attacks: A resting-state functional MRI study.},
  author={Faisal Mohammad Amin and Anders Hougaard and Stefano Magon and Mohammad Sohail Asghar and Nur Nabil Ahmad and Egill Rostrup and Till Sprenger and Messoud Ashina},
  journal={Neurology},
  year={2016},
  volume={86 2},
  pages={180-7}
}
OBJECTIVE To investigate resting-state functional connectivity in the salience network (SN), the sensorimotor network (SMN), and the default mode network (DMN) during migraine attacks induced by pituitary adenylate cyclase-activating polypeptide-38 (PACAP38). METHODS In a double-blind, randomized study, 24 female migraine patients without aura received IV PACAP38 or vasoactive intestinal polypeptide (VIP) over 20 minutes. Both peptides are closely related and cause vasodilation, but only… CONTINUE READING