## In silico prediction of the mutagenicity of nitroaromatic compounds using a novel two-QSAR approach.

- Yi-Lung Ding, You-Chen Lyu, Max K Leong
- Toxicology in vitro : an international journalâ€¦
- 2017

Highly Influenced

@article{Topliss1979ChanceFI, title={Chance factors in studies of quantitative structure-activity relationships.}, author={J G Topliss and Robert Edwards}, journal={Journal of medicinal chemistry}, year={1979}, volume={22 10}, pages={1238-44} }

- Published 1979 in Journal of medicinal chemistry

Multiple regression analysis is a basic statistical tool used for QSAR studies in drug design. However, there is a risk or arriving at fortuitous correlations when too many variables are screened relative to the number of available observations. In this regard, a critical distinction must be made between the number of variables screened for possibleâ€¦Â CONTINUE READING

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