Chance and necessity do not explain the origin of life

@article{Trevors2004ChanceAN,
  title={Chance and necessity do not explain the origin of life},
  author={J. T. Trevors and David Abel},
  journal={Cell Biology International},
  year={2004},
  volume={28}
}
  • J. Trevors, D. Abel
  • Published 1 November 2004
  • Biology, Medicine
  • Cell Biology International
Where and how did the complex genetic instruction set programmed into DNA come into existence? The genetic set may have arisen elsewhere and was transported to the Earth. If not, it arose on the Earth, and became the genetic code in a previous lifeless, physical—chemical world. Even if RNA or DNA were inserted into a lifeless world, they would not contain any genetic instructions unless each nucleotide selection in the sequence was programmed for function. Even then, a predetermined… 
MORE THAN METAPHOR: GENOMES ARE OBJECTIVE SIGN SYSTEMS
Genetic cybernetics preceded human consciousness in its algorithmic programming and control. Nucleic acid instructions reside in linear, resortable, digital, and unidirectionally read sign sequences.
The GS (genetic selection) Principle.
  • D. Abel
  • Medicine, Biology
    Frontiers in bioscience
  • 2009
The GS (Genetic Selection) Principle states that biological selection must occur at the nucleotide-sequencing molecular-genetic level of 3'5' phosphodiester bond formation. After-the-fact
Self-Referential Formation of the Genetic System
TLDR
It is indicated that The Last Universal Common Ancestor populations could, at some early stages, be composed of lineages bearing similar genetic codes, due to the simple and highly deterministic character of the process.
Thermosynthesis as energy source for the RNA World: a new model for the origin of life
The thermosynthesis concept, biological free energy gain from thermal cycling, is combined with the concept of the RNA World. The resulting overall origin of life model gives new explanations for the
A self-referential model for the formation of the genetic code
TLDR
The model indicates that genetic information emerged during the process of formation of the coding/decoding system and that genes were defined by the proteins.
Is Life Unique?
  • D. Abel
  • Computer Science, Medicine
    Life
  • 2011
Is life physicochemically unique? No. Is life unique? Yes. Life manifests innumerable formalisms that cannot be generated or explained by physicodynamics alone. Life pursues thousands of
Information and Thermodynamics in Living Systems
Are there laws of information exchange? And how do the principles of thermodynamics connect with the communication of information? We consider first the concept of information and examine the various
Thermosynthesis as energy source for the RNA World: a model for the bioenergetics of the origin of life.
The thermosynthesis concept, biological free energy gain from thermal cycling, is combined with the concept of the RNA World. The resulting overall origin of life model suggests new explanations for
Genome increase as a clock for the origin and evolution of life
  • A. Sharov
  • Biology, Medicine
    Biology Direct
  • 2006
TLDR
The increase of functional non-redundant genome size in macro-evolution was consistent with the exponential hypothesis, and the possibility of panspermia as a source of life on earth should be discussed on equal basis with alternative hypotheses of de-novo life origin.
Biological function and the genetic code are interdependent
Life never ceases to astonish scientists as its secrets are more and more revealed. In particular the origin of life remains a mystery. One wonders how the scientific community could unravel a
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 184 REFERENCES
2 Prospects for Understanding the Origin of the RNA World
TLDR
The general idea that, in the development of life on the earth, evolution based on RNA replication preceded the appearance of protein synthesis was first proposed about 30 years ago and the existence of an RNA World as a precursor of the authors' DNA/protein world is a hypothesis.
1 Prospects for Understanding the Origin of the RNA World
TLDR
The existence of an RNA world as a precursor of the authors' DNA/protein world is a hypothesis and three basic assumptions are included: At some time in the evolution of life, genetic continuity was assured by the replication of RNA; Watson-Crick base-pairing was the key to replication; and genetically encoded proteins were not involved as catalysts.
Co-evolution of the genetic code and ribozyme replication.
TLDR
By pursuing this model, the START and STOP codons were derived and their original function with regard to the primitive 23S ribosomal RNA is suggested.
Hypercycles and the origin of life
TLDR
The central problem discussed in a series of papers by Manfred Eigen and Peter Schuster proposing the ‘hypercycle’ as a necessary intermediate stage is that one cannot have accurate replication without a length of RNA, say, 2000 or more base pairs, and one cannotHave that much RNA without accurate replication.
The non-universality of the genetic code: the universal ancestor was a progenote.
TLDR
The coevolution theory of genetic code origin (Wong, J.T.A. 1975), based on the strict parallelism of the biosynthetic relationships between amino acids and the organization of the genetic code and postulates that these relationships were mediated by tRNA-like molecules on which the biosynthesis transformations between precursor and product amino acids took place, is assumed to be substantially correct.
A Replicator Was Not Involved in the Origin of Life
TLDR
The possibility that formation of the first replicator took place through a very improbable event cannot be excluded, but greater attention should be given to metabolism‐first theories, which avoid this difficulty.
Testing a biosynthetic theory of the genetic code: fact or artifact?
TLDR
It is shown that coevolution theory cannot adequately explain the structure of the genetic code because the theory's definition of "precursor-product" amino acid pairs is unjustified biochemically because it requires the energetically unfavorable reversal of steps in extant metabolic pathways to achieve desired relationships.
Origin of Life on Earth and Shannon's Theory of Communication
  • H. Yockey
  • Computer Science, Medicine
    Comput. Chem.
  • 2000
TLDR
It is highly relevant to the origin of life that the genetic code is constructed to confront and solve the problems of communication and recording by the same principles found both in the genetic information system and in modern computer and communication codes.
The Case for an Error Minimizing Standard Genetic Code
TLDR
There remain ill explored facets of the `error minimizing' code hypothesis, including the mechanism and pathway by which an adaptive pattern of codon assignments emerged, the extent to which natural selection created synonym redundancy, its role in shaping the amino acid and nucleotide languages, and even the correct interpretation of the adaptive codon assignment pattern.
Evolution of the genetic code.
  • B. K. Davis
  • Biology, Medicine
    Progress in biophysics and molecular biology
  • 1999
TLDR
Findings on the genetic code provide empirical evidence, from a contemporaneous source, that a surface reaction network, centred on C-fixing autocatalytic cycles, rapidly led to cellular life on Earth.
...
1
2
3
4
5
...