Chance and Necessity in Evolution: Lessons from RNA

Abstract

The RNA folding map, understood as the relationship between sequences and secondary structures or shapes, exhibits robust statistical properties summarized by three notions: (1) the notion of a typical shape (that among all sequences of fixed length certain shapes are realized much more frequently than others), (2) the notion of shape space covering (that… (More)
DOI: 10.1016/S0167-2789(99)00076-7

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