Challenging differential diagnosis of a wild-type gastrointestinal stromal tumour (GIST) or rare reticular perineurioma of the stomach? The role for mutational analysis.

@article{Richter2011ChallengingDD,
  title={Challenging differential diagnosis of a wild-type gastrointestinal stromal tumour (GIST) or rare reticular perineurioma of the stomach? The role for mutational analysis.},
  author={Konrad Klaus Richter and Alexander Dempster and Angelo Paolo dei Tos and Rakesh Premkumar and Christopher Jackson},
  journal={The New Zealand medical journal},
  year={2011},
  volume={124 1331},
  pages={45-55}
}
The differential diagnosis of submucosal stomach lesions includes gastrointestinal stromal tumour (GIST), leiomyoma, synovial sarcomas, perineurioma, myxoid chondrosarcoma, myoepithelial tumour and other rare mesenchymal tumours. GISTs are well-defined lesions with distinctive morphologic and histogenetic characteristics that show 95% positive staining for CD117. Differential diagnosis of wild-type GISTs can be challenging. Here, we present two stomach tumours that were operated on in our… CONTINUE READING