Challenging Regional Psoriasis and Ustekinumab Biotherapy: Impact of the Patterns of Disease

@inproceedings{HermannsL2012ChallengingRP,
  title={Challenging Regional Psoriasis and Ustekinumab Biotherapy: Impact of the Patterns of Disease},
  author={Trinh Hermanns-L{\^e} and Enzo Berardesca and G{\'e}rald E. Pi{\'e}rard and Marianne Lesuisse and C Pi{\'e}rard-franchimont},
  booktitle={Journal of biomedicine & biotechnology},
  year={2012}
}
In some patients, psoriasis appears refractory to many treatments, particularly when the disease is confined to some specific body regions. In this respect, palmoplantar psoriasis and palmoplantar pustulosis are possibly related conditions in their immunopathomechanisms involving Il-12, IL-23, and Th17. Nail psoriasis and scalp psoriasis are two other particular psoriasis manifestations. Accordingly, ustekinumab was tested in a few of these patients. The present paper is limited to peer… CONTINUE READING

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Nail surface topography and onychochronobiology

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