Challenges with the diagnosis and treatment of cerebral radiation necrosis.

  title={Challenges with the diagnosis and treatment of cerebral radiation necrosis.},
  author={Samuel Tay Chao and Manmeet Singh Ahluwalia and Gene H. Barnett and Glen H. J. Stevens and E. B. Murphy and Abigail Lauren Stockham and Kevin Shiue and John H. Suh},
  journal={International journal of radiation oncology, biology, physics},
  volume={87 3},
The incidence of radiation necrosis has increased secondary to greater use of combined modality therapy for brain tumors and stereotactic radiosurgery. Given that its characteristics on standard imaging are no different that tumor recurrence, it is difficult to diagnose without use of more sophisticated imaging and nuclear medicine scans, although the accuracy of such scans is controversial. Historically, treatment had been limited to steroids, hyperbaric oxygen, anticoagulants, and surgical… CONTINUE READING