Challenges in the treatment of Rheumatoid Arthritis.

@article{Conigliaro2019ChallengesIT,
  title={Challenges in the treatment of Rheumatoid Arthritis.},
  author={Paola Conigliaro and Paola Triggianese and Erica De Martino and Giulia Lavinia Fonti and Maria Sole Chimenti and Flavia Sunzini and Alessandra Viola and Claudia Canofari and Roberto Perricone},
  journal={Autoimmunity reviews},
  year={2019},
  volume={18 7},
  pages={
          706-713
        }
}
Rheumatoid Arthritis (RA) is a chronic inflammatory disease characterized by a heterogeneous clinical response to the different treatments. Some patients are difficult to treat and do not reach the treatment targets as clinical remission or low disease activity. Known negative prognostic factors, such as the presence of auto-antiantibodies and joint erosion, the presence of a genetic profile, comorbidities and extra-articular manifestations, pregnancy or a pregnancy wish may concur to the… 
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