Challenges in the analytical characterization of PEGylated asparaginase

@inproceedings{Brandenburg2020ChallengesIT,
  title={Challenges in the analytical characterization of PEGylated asparaginase},
  author={Gunda Brandenburg and Sabine Poppenborg and Christoph Radcke and Julia G. Wittmann and Ralf Kr{\"a}hmer and Gianfranco Pasut and Frank Leenders},
  year={2020}
}
2 Citations
Cancer Nanomedicine and Immune System—Interactions and Challenges
TLDR
The interactions between an approved cancer nanomedicine with TME immunology is reviewed and the challenges that need to be addressed for the full clinical potential of ongoing cancer Nanomedicines despite the encouraging preclinical data are discussed.
Integrated Lab-Scale Process Combining Purification and PEGylation of l-Asparaginase from Zymomonas mobilis
During the last quarter of a century, PEGylation has been used to enhance the clinical effectiveness of various therapeutic proteins. However, the conjugation process significantly increases the co...

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