Challenges in radiobiological modeling: can we decide between LQ and LQ-L models based on reviewed clinical NSCLC treatment outcome data?

@inproceedings{Santiago2016ChallengesIR,
  title={Challenges in radiobiological modeling: can we decide between LQ and LQ-L models based on reviewed clinical NSCLC treatment outcome data?},
  author={A. D{\'i}az-De Santiago and Steffen Barczyk and Urszula Jelen and R. Engenhart-Cabillic and Andrea Wittig},
  booktitle={Radiation oncology},
  year={2016}
}
AIM To study the dose-response of stage I non-small-cell lung cancer (NSCLC) in terms of long-term local tumor control (LC) after conventional and hypofractionated photon radiotherapy, modeled with the linear-quadratic (LQ) and linear-quadratic-linear (LQ-L) approaches and to estimate the clinical α/β ratio within the LQ frame. MATERIAL AND METHODS We identified studies of curative radiotherapy as single treatment through MedLine search reporting 3-year LC as primary outcome of interest… CONTINUE READING
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