Challenges in defining type 2M von Willebrand disease: results from a Canadian cohort study

@article{James2007ChallengesID,
  title={Challenges in defining type 2M von Willebrand disease: results from a Canadian cohort study},
  author={P. James and C. Notley and C. Hegadorn and M. Poon and I. Walker and D. Rapson and D. Lillicrap},
  journal={Journal of Thrombosis and Haemostasis},
  year={2007},
  volume={5}
}
Summary.  Background/methods: In order to better characterize the genotype–phenotype correlation in type 2M von Willebrand disease (VWD), we sequenced the coding region for the mature subunit of the von Willebrand factor (VWF) gene (exons 18–52, including exon/intron boundaries) in 16 index cases originally submitted to the Canadian Type 1 VWD Study as type 1 VWD, but reclassified as type 2M VWD on the basis of phenotype (excessive mucocutaneous bleeding and von Willebrand factor: antigen (VWF… Expand
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References

SHOWING 1-10 OF 53 REFERENCES
Genetic linkage and association analysis in type 1 von Willebrand disease: results from the Canadian Type 1 VWD Study
Diagnosis of inherited von Willebrand disease: a clinical perspective.
  • A. Federici
  • Medicine
  • Seminars in thrombosis and hemostasis
  • 2006
...
1
2
3
4
5
...