Challenges in circulating tumour cell research

@article{AlixPanabires2014ChallengesIC,
  title={Challenges in circulating tumour cell research},
  author={Catherine Alix-Panabi{\`e}res and Klaus Pantel},
  journal={Nature Reviews Cancer},
  year={2014},
  volume={14},
  pages={623-631}
}
During the past ten years, circulating tumour cells (CTCs) have received enormous attention as new biomarkers and the subject of basic research. Although CTCs are already used in numerous clinical trials, their clinical utility is still under investigation. Many issues regarding the detection and characterization of CTCs remain unknown. In this Opinion article, we propose a conceptual framework of CTC assays and point out current challenges of CTC research, which might structure this dynamic… CONTINUE READING
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