Challenges in assessing microbial susceptibility and predicting clinical response to newer-generation fluoroquinolones.

@article{Segreti2012ChallengesIA,
  title={Challenges in assessing microbial susceptibility and predicting clinical response to newer-generation fluoroquinolones.},
  author={John A Segreti and Ronald N. Jones and Joseph S. Bertino},
  journal={Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics},
  year={2012},
  volume={28 1},
  pages={3-11}
}
PURPOSE To determine the most appropriate methods for assessing the potential effectiveness of the newer topical fluoroquinolones gatifloxacin, moxifloxacin, and besifloxacin. METHODS This article is based on a literature search for published articles about the pharmacokinetic (PK) and pharmacodynamic (PD) characteristics of and measure of bacterial susceptibility to topical ophthalmic fluoroquinolones. Search terms included fluoroquinolones, susceptibility, resistance, minimal/minimum… CONTINUE READING

References

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Ocular pharmacokinetics/pharmacodynamics of besifloxacin, moxifloxacin, and gatifloxacin following topical administration to pigmented rabbits.

Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics • 2010

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