The Large Hadron Collider (LHC) is a proton-proton collider with a center-of-mass energy of 14 TeV, currently under construction at CERN, Geneva. At the time of this conference , the LHC was still planning to have an engineering run in the fall of 2007, in order to establish single beam operation at the injection energy of 450 GeV, and provide first collisions at fairly low luminosity, at 900 GeV center-of-mass energy . The first collisions at √ s = 14 TeV could occur in spring 2008, and with a steadily increasing luminosity during the next 26 weeks of protonproton running, the ATLAS and CMS experiments might collect an integrated luminosity close to 1 fb by the end of 2008. In order to be able to present first results at Moriond 2009, ATLAS and CMS face a number of challenges, some of which will be discussed in this paper. Hereby we will focus on four examples of possible signs of new physics in first data.