Challenges and opportunities in the development of therapeutics for chronic kidney disease.

C hronic kidney disease (CKD) is any condition causing a reduction in kidney function over time. In practical terms, CKD is present when the estimated glomerular filtration rate (eGFR) is at stage 3 or less than 60 mL/min for a period of greater than 3 months. As defined, greater than 20 million adults in the United States have some level of CKD. Since 1986… CONTINUE READING