Challenges and Opportunities of Nanotechnology as Delivery Platform for Tocotrienols in Cancer Therapy

@inproceedings{Maniam2018ChallengesAO,
  title={Challenges and Opportunities of Nanotechnology as Delivery Platform for Tocotrienols in Cancer Therapy},
  author={Geetha Maniam and C. Kiran Mai and Mohd Zulkefeli and Christine Duf{\`e}s and Doryn Meam-Yee Tan and Ju-Yen Fu},
  booktitle={Front. Pharmacol.},
  year={2018}
}
Plant-derived phytonutrients have emerged as health enhancers. Tocotrienols from the vitamin E family gained high attention in recent years due to their multi-targeted biological properties, including lipid-lowering, neuroprotection, anti-inflammatory, antioxidant, and anticancer effects. Despite well-defined mechanism of action as an anti-cancer agent, their clinical use is hampered by poor pharmacokinetic profile and low oral bioavailability. Delivery systems based on nanotechnology were… CONTINUE READING
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