Challenge tests: assessment of the noradrenergic and GABA systems in depression and anxiety disorders.

@article{Coupland1992ChallengeTA,
  title={Challenge tests: assessment of the noradrenergic and GABA systems in depression and anxiety disorders.},
  author={Nick Coupland and Paul W Glue and David J. Nutt},
  journal={Molecular aspects of medicine},
  year={1992},
  volume={13 3},
  pages={221-47}
}
A variety of methods have been developed for the study of noradrenergic and GABA systems in health and disease in man. These include measurements of neurotransmitters in peripheral blood and CSF; studies of neuronal anatomy, neurotransmitter levels and receptor binding in post-mortem brain tissue; measures of binding and function in peripheral receptors, which may model those in the brain; characterisation of the genes and their products involved in neurotransmission; and scanning techniques… CONTINUE READING