Chalcones, coumarins, and flavanones from the exudate of Angelica keiskei and their chemopreventive effects.

@article{Akihisa2003ChalconesCA,
  title={Chalcones, coumarins, and flavanones from the exudate of Angelica keiskei and their chemopreventive effects.},
  author={Toshihiro Akihisa and Harukuni Tokuda and Motohiko Ukiya and Masao Iizuka and Stefan Schneider and Kazuya Ogasawara and Teruo Mukainaka and Kenji Iwatsuki and Takashi Suzuki and Hoyoku Nishino},
  journal={Cancer letters},
  year={2003},
  volume={201 2},
  pages={133-7}
}
From an ethyl acetate-soluble fraction of the exudate obtained from the stems of Angelica keiskei (Umbelliferae), 17 compounds, viz. five chalcones (1-5), seven coumarins (6-12), three flavanones (13-15), one diacetylene (16), and one 5-alkylresorcinol (17), were isolated. These compounds were evaluated with respect to their inhibitory effects on the induction of Epstein-Barr virus early antigen (EBV-EA) by 12-O-tetradecanoylphorbol-13-acetate (TPA) in Raji cells, which is known to be a primary… CONTINUE READING