Chagas' disease.

  title={Chagas' disease.},
  author={Herbert B Tanowitz and Louis V. Kirchhoff and Dietrich Simon and Stephen A. Morris and Louis M Weiss and Monika Wittner},
  journal={Clinical microbiology reviews},
  volume={5 4},
Chagas' disease, caused by Trypanosoma cruzi, is an important cause of morbidity in many countries in Latin America. The important modes of transmission are by the bite of the reduviid bug and blood transfusion. The organism exists in three morphological forms: trypomastigotes, amastigotes, and epimastigotes. The mechanism of transformation and differentiation is currently being explored, and signal transduction pathways of the parasites may be involved in this process. Parasite adherence to… CONTINUE READING


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