Chagas' disease: trends in immunological research and prospects for immunoprophylaxis.

@article{Teixeira1979ChagasDT,
  title={Chagas' disease: trends in immunological research and prospects for immunoprophylaxis.},
  author={Antonio R. L. Teixeira},
  journal={Bulletin of the World Health Organization},
  year={1979},
  volume={57 5},
  pages={697-710}
}
Acute infection with Trypanosoma cruzi usually subsides spontaneously but the mortality rate encountered in individuals with the chronic infection is high. Much evidence has accumulated in the last five years that autoimmunity plays an important role in the pathogenesis of the myocarditis that is common in the chronic phase. A negative relationship has been observed between the demonstrable parasitaemia and the presence of severe cardiac lesions. This myocarditis is characterized by lymphocytic… CONTINUE READING
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