Cgrp May Play A Causative Role in Migraine

  title={Cgrp May Play A Causative Role in Migraine},
  author={L. H. Lassen and PA Haderslev and V. B. Jacobsen and H. K. Iversen and Bj{\o}rn Sperling and Jes Olesen},
  pages={54 - 61}
Calcitonin gene-related peptide (CGRP) has been detected in increased amounts in external jugular venous blood during migraine attacks. However, it is unknown whether this is secondary to migraine or whether CGRP may cause headache. In a double-blind crossover study, the effect of human αCGRP (2 μg/min) or placebo infused intravenously for 20 min was studied in 12 patients suffering from migraine without aura. Headache intensity was scored on a scale from 0 to 10. Two patients were excluded due… 

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No increase of calcitonin gene–related peptide in jugular blood during migraine

Previous findings of increased CGRP level in external jugular or cubital fossa venous blood could not be confirmed and this finding strongly suggests that C GRP is not increased in jugular venousBlood during migraine without aura.

Calcitonin gene related peptide (CGRP)–provoked migraine-like attacks

  • F. CutrerP. Mathew
  • Psychology, Medicine
    Cephalalgia : an international journal of headache
  • 2010
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