Cervical intervertebral disc degeneration induced by unbalanced dynamic and static forces: a novel in vivo rat model.

@article{Wang2006CervicalID,
  title={Cervical intervertebral disc degeneration induced by unbalanced dynamic and static forces: a novel in vivo rat model.},
  author={Yongjun Wang and Qi Shi and William Weijia Lu and Ken Cheung and Michael Darowish and Tian-fang Li and Yu-Feng Dong and Chong-jian Zhou and Quan Zhou and Zhi-Jun Hu and Mei Lun Liu and Qin Bian and Chen-guang Li and Keith Kei Dip Luk and John Chiyan Leong},
  journal={Spine},
  year={2006},
  volume={31 14},
  pages={1532-8}
}
STUDY DESIGN Establishment of a novel in vivo animal model of cervical spondylosis. OBJECTIVE To investigate apoptotic, degenerative, and inflammatory changes occurring in the cervical intervertebral discs of rats. SUMMARY OF BACKGROUND DATA Cervical degeneration occurs as the result of imbalance of both static and dynamic spinal stabilizers. The disc degeneration that occurs is characterized by increased local inflammation and increased apoptosis of intervertebral disc cells. METHODS By… CONTINUE READING

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