Cervical carcinoma after negative Pap smears: evidence against rapid-onset cancers.

@article{Wain1992CervicalCA,
  title={Cervical carcinoma after negative Pap smears: evidence against rapid-onset cancers.},
  author={Gerard Vincent Wain and Annabelle Farnsworth and Neville F. Hacker},
  journal={International journal of gynecological cancer : official journal of the International Gynecological Cancer Society},
  year={1992},
  volume={2 6},
  pages={
          318-22
        }
}
Recently, suggestions have been made that a 'rapid-onset' type of cervical cancer is emerging. Evidence for this entity is based on the diagnosis of invasive cervical carcinoma within 2 or 3 years of a 'normal' Pap smear. Analysis of 237 patients presenting to our unit between November 1986 and July 1990 with the histologic diagnosis of invasive carcinoma of the cervix revealed 51 patients (21.5%) who reported having had a 'normal' Pap smear within 2 years of diagnosis. Strenuous efforts were… CONTINUE READING
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