Cervical Dystonia

@article{Velickovic2012CervicalD,
  title={Cervical Dystonia},
  author={M. Velickovic and R. Benabou and M. Brin},
  journal={Drugs},
  year={2012},
  volume={61},
  pages={1921-1943}
}
Dystonia is a syndrome of sustained involuntary muscle contractions, frequently causing twisting and repetitive movements or abnormal posturing. Cervical dystonia (CD) is a form of dystonia that involves neck muscles. However, CD is not the only cause of neck rotation. Torticollis may be caused by orthopaedic, musculofibrotic, infectious and other neurological conditions that affect the anatomy of the neck, and structural causes.It is estimated that there are between 60 000 and 90 000 patients… Expand
A Case of Cervical Dystonia with Non Responsive To Usual Noninvasive Treatment
TLDR
A rare case of a forty seven year old male patient with a history of cervical dystonia presented with struggle with head position, resisting but never overcoming the tendency of his head to assume an unnatural position, and drugs including oral analgesic, muscle relaxant, anti-Parkinson drug & even antipsychotic drug failed. Expand
Cervical Myeloradiculopathy and Atlantoaxial instability in Cervical Dystonia.
TLDR
Early-onset cervical dystonia can lead to cord complications at a young age and at higher levels of the cervical spine and at cervicovertebral junction, and comprehensive management by a multidisciplinary team is crucial. Expand
Anterocollis and anterocaput
TLDR
The diagnosis is based on the clinical presentation, needle-electromyography to identify affected muscles and rule out other conditions, X-ray of the cervical/thoracic spine, and cerebral MRI, which shows tonic or tremulous head-movements and neck-posturing. Expand
Effect of Neck Botulinum Neurotoxin Injection on Proprioception and Somatosensory-Motor Cortical Processing in Cervical Dystonia
TLDR
Wrist proprioceptive perception during passive/active movements is abnormal in CD, and an excessive rise of premotor/motor cortical β-oscillations during motor planning is associated with this proprioception dysfunction. Expand
Cervical Dystonia Refractory to Botulinum Toxin Responding to Radiofrequency Ablation: A Case Report
TLDR
It is suggested that large-scale research is required to postulate whether CD patients, whose symptoms are refractory to botulinum toxin, should be routinely screened for cervical facet arthropathy. Expand
Dystonia and the cerebellum: A new field of interest in movement disorders?
TLDR
It is proposed that dystonia is a large-scale dysfunction, involving not only cortico-basal ganglia-thalamo-cortical pathways, but the cortICO-ponto-cerebello-thalAMCortical loop as well. Expand
The therapeutic usage of botulinum toxin (Botox) in non-cosmetic head and neck conditions – An evidence based review
  • K. Awan
  • Medicine
  • Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
  • 2017
TLDR
There is compelling evidence in the published literature to demonstrate the beneficial role of Botox in a wide range of non-cosmetic conditions pertaining to the head and neck (mainly level 1 evidence). Expand
Hemifacial spasm in sleep – A polysomnographic study
TLDR
This study confirms the continuity of hyperkinetic movements of HFS during sleep despite a significant decrease compared to wakefulness causing increased arousals. Expand
Accuracy of Ultrasound-Guided and Non-guided Botulinum Toxin Injection Into Neck Muscles Involved in Cervical Dystonia: A Cadaveric Study
Objective To compare the accuracy of ultrasound-guided and non-guided botulinum toxin injections into the neck muscles involved in cervical dystonia. Methods Two physicians examined six musclesExpand
Drug-Induced Parkinsonism and Abnormal Involuntary Movements
Motor side effects emerging from the use of neuroleptics have been recognised since their first use in the 1950s. There is however an increasing awareness that other drug classes (in particular otherExpand
...
1
2
...

References

SHOWING 1-10 OF 264 REFERENCES
Treatment of dystonia
TLDR
Although pathogenesis-targeted treatment is still elusive, the currently available symptomatic treatment strategies are quite effective for some types of dystonia in relieving involuntary movements, correcting abnormal posture, preventing contractures, reducing pain, and improving function and quality of life. Expand
Modification of cervical dystonia by selective sensory stimulation
TLDR
It is concluded that selective sensory stimulation can beneficially modify cervical dystonia in some patients and warrant further investigation of the use of sensory stimulation for control of cervical dySTONia. Expand
Idiopathic cervical dystonia: Clinical characteristics
TLDR
Because the cervical dystonia in 38% of patients is not spasmodic, it is proposed that the term “spas modic torticollis” is not a completely appropriate designation for this condition. Expand
Trick maneuvers in cervical dystonia: Investigation of movement‐ and touch‐related changes in polymyographic activity
TLDR
Results might indicate different physiological mechanisms in clinically indistinguishable antagonistic gestures in cervical dystonia patients with idiopathic CD. Expand
Evaluation and Treatment of Dystonia
  • B. Scott
  • Medicine
  • Southern medical journal
  • 2000
TLDR
A variety of treatments can give symptomatic benefit in dystonia, but appropriate treatment requires proper diagnosis of the condition. Expand
A pilot trial of clozapine in the treatment of cervical dystonia
TLDR
The efficacy of clozapine in the treatment of severe forms of cervical dystonia was tested using the Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS) and the severity and characteristics of dySTONia were evaluated. Expand
Cervical dystonia
TLDR
Anticholinergic drugs provided moderate improvement in 33% of patients, but local intramuscular botulinum toxin injections relieved CD, local pain, or both in over 90% of all treated patients. Expand
Comparison of acute‐ and delayed‐onset posttraumatic cervical dystonia
  • D. Tarsy
  • Medicine
  • Movement disorders : official journal of the Movement Disorder Society
  • 1998
TLDR
Delayed‐onset cervical dystonia was characterized by markedly reduced cervical mobility; prominent shoulder elevation with trapezius hypertrophy in most patients, absence of involuntary movements, sensory tricks, or activation maneuvers; and poor response to botulinum toxin injection, which was clinically indistinguishable from nontraumatic idiopathic cervical dySTONia. Expand
Localized injections of botulinum toxin for the treatment of focal dystonia and hemifacial spasm
  • M. Brin, S. Fahn, +8 authors D. McMahon
  • Medicine
  • Movement disorders : official journal of the Movement Disorder Society
  • 1987
TLDR
This approach of chemically weakening contracting muscles in focal dystonia offers many advantages over pharmacotherapy and surgical therapy, and additional experience is needed to explore the proper doses, and potential for long term adverse effects. Expand
Pain in spasmodic torticollis
TLDR
It is suggested that pain associated with spasmodic torticollis does not arise in muscles alone, and it is hypothesised that central mechanisms are also involved. Expand
...
1
2
3
4
5
...