Ceruloplasmin and iron in Alzheimer’s disease and Parkinson’s disease: a synopsis of recent studies

@inproceedings{Kristinsson2012CeruloplasminAI,
  title={Ceruloplasmin and iron in Alzheimer’s disease and Parkinson’s disease: a synopsis of recent studies},
  author={Jakob Kristinsson and J{\'o}n Snaedal and Gudlaug T{\'o}rsd{\'o}ttir and Torkell J{\'o}hannesson},
  booktitle={Neuropsychiatric disease and treatment},
  year={2012}
}
Ceruloplasmin (Cp) concentration and oxidative activity in serum are lowered in Parkinson's disease (PD). In most PD patients, iron increases in the substantia nigra in the midbrain. In PD, the low Cp concentration and activity in serum and the high iron amounts in the substantia nigra appears to be correlated. An hereditary background is common in PD and variations in the Cp gene that have been found in PD are associated with high iron levels in the substantia nigra. Variations in Cp synthesis… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 21 CITATIONS

The Aging of Iron Man

VIEW 1 EXCERPT
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 54 REFERENCES

Iron toxicity in diseases of aging: Alzheimer's disease, Parkinson's disease and atherosclerosis.

VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

Ceruloplasmin in neurodegenerative diseases.

VIEW 9 EXCERPTS
HIGHLY INFLUENTIAL