Cerebrovascular responses to CO2 after inhibition of sympathetic activity.

  title={Cerebrovascular responses to CO2 after inhibition of sympathetic activity.},
  author={A L L{\'o}pez de Pablo and Manuel C Gonzalez and Godofredo Di{\'e}guez and Bernardino G{\'o}mez and Salvador Lluch},
  journal={Journal of applied physiology: respiratory, environmental and exercise physiology},
  volume={53 4},
The effects of inhalation of 10% CO2 in air on cerebral blood flow (CBF) and cerebrovascular resistance (CVR) were examined in 13 unanesthetized goats before and after impairment of the sympathetic activity present in cerebral vessels. Under control conditions, inhalation of CO2 increased CBF from 112 +/- 10.2 (SE) to 191 +/- 17.2 ml X min-1 X 100 g-1 and decreased CVR from 0.91 +/- 0.02 to 0.55 +/- 0.03 Torr X ml-1 X min X 100 g. After treatment with reserpine CO2 increased CBF to levels… CONTINUE READING