Cerebrovascular reactivity to acetazolamide in carotid artery disease. Enhancement of side-to-side CBF asymmetry indicates critically reduced perfusion pressure.

@article{Schroeder1986CerebrovascularRT,
  title={Cerebrovascular reactivity to acetazolamide in carotid artery disease. Enhancement of side-to-side CBF asymmetry indicates critically reduced perfusion pressure.},
  author={Tobias Schroeder},
  journal={Neurological research},
  year={1986},
  volume={8 4},
  pages={231-6}
}
Cerebral blood flow (CBF), measured with a mobile 10 detector unit and non-invasive Xenon-133 technique, was investigated before and after cerebral vasodilation with acetazolamide (Diamox) in 78 patients prior to carotid endarterectomy. The change in side-to-side CBF asymmetry from baseline to Diamox study, the Diamox asymmetry enhancement, was compared with the intraoperatively measured cerebral perfusion pressures. Asymmetry enhancement exceeded the methodological variation in 14 patients, 13… CONTINUE READING