Cerebrovascular reactivity and dynamic autoregulation in ischaemic subcortical white matter disease.

@article{Birns2009CerebrovascularRA,
  title={Cerebrovascular reactivity and dynamic autoregulation in ischaemic subcortical white matter disease.},
  author={Jonathan Birns and Jerzy Jarosz and Hugh S. Markus and Lalit Kalra},
  journal={Journal of neurology, neurosurgery, and psychiatry},
  year={2009},
  volume={80 10},
  pages={
          1093-8
        }
}
BACKGROUND It has been suggested that impaired cerebral autoregulation and vasodilatory capacity may play in role in the pathogenesis of the leukoaraiosis seen in small vessel disease. Adequate perfusion of the deep white matter of the brain depends on the relationships between blood pressure (BP), cerebral vasoreactivity and autoregulation. METHODS 24 h ambulatory BP measurement, quantitative volumetric MRI analysis of white matter lesion (WML) volume and transcranial Doppler ultrasound… CONTINUE READING

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