Cerebrovascular reactivity and cerebral autoregulation in normal subjects.

  title={Cerebrovascular reactivity and cerebral autoregulation in normal subjects.},
  author={Emmanuel Carrera and Leslie K Lee and Sotirios Giannopoulos and Randolph S. Marshall},
  journal={Journal of the neurological sciences},
  volume={285 1-2},
BACKGROUND Cerebrovascular reactivity (CVR) testing with CO2 challenge is used clinically as a measure of cerebrovascular reserve. However it is not known whether CVR measures the same physiological process as spontaneous cerebral autoregulation (CA). PURPOSE To compare CVR with CA in healthy volunteers, using continuous monitoring of cerebral blood flow velocity (CBFV) and arterial blood pressure (ABP). METHODS We prospectively studied CVR and CA in 18 healthy volunteers. CVR was assessed… CONTINUE READING