Cerebrovascular events in sickle cell-beta thalassemia treated with hydroxyurea: a single center prospective survey in adult Italians.

@article{Rigano2013CerebrovascularEI,
  title={Cerebrovascular events in sickle cell-beta thalassemia treated with hydroxyurea: a single center prospective survey in adult Italians.},
  author={Paolo Rigano and Alice Pecoraro and Giuseppina Calvaruso and Martin H Steinberg and Sonia Iannello and Aurelio Maggio},
  journal={American journal of hematology},
  year={2013},
  volume={88 11},
  pages={E261-4}
}
Stroke is a common cause of morbidity and mortality in sickle cell disease (SCD) and silent cerebral infarction is the most common form of neurologic injury. The frequency and risk factors for new silent cerebral infarction are incompletely understood. Moreover, no recommended treatment has been established. Although hydroxyurea (HU) is recommended for SCD, concerns remain regarding its role in the prevention of cerebrovascular events, including silent cerebral infarction. A single center… CONTINUE READING
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