Cerebrovascular damage as a cause for Alzheimer's disease.

  title={Cerebrovascular damage as a cause for Alzheimer's disease.},
  author={Christian Humpel and Josef J. M. Marksteiner},
  journal={Current neurovascular research},
  volume={2 4},
Alzheimer's disease is a progressive brain disorder that gradually destroys a patient's memory function and ability to carry out daily activities. According to the prevailing amyloid cascade hypothesis, Alzheimer's disease is initiated by amyloid beta-peptide accumulation leading to neuronal toxicity. The neurofibrillary tangle deriving from hyperphosphorylated tau and synapse loss are also key features for Alzheimer's disease. Recent studies revealed a significant co-morbidity of Alzheimer's… CONTINUE READING


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