Cerebrovascular complications and parvovirus infection in homozygous sickle cell disease.

@article{Wierenga2001CerebrovascularCA,
  title={Cerebrovascular complications and parvovirus infection in homozygous sickle cell disease.},
  author={Klaas J Wierenga and Beryl E Serjeant and Graham R. Serjeant},
  journal={The Journal of pediatrics},
  year={2001},
  volume={139 3},
  pages={
          438-42
        }
}
Human parvovirus B19 infection causes most clinically defined aplastic crises in homozygous sickle cell (SS) disease. With transfusion support, the outcome is generally benign; however, cerebrovascular complications in close temporal association with B19-induced aplastic crises have been described. We carried out a retrospective review, between 1978 and 1999, of 346 aplastic crises in patients with SS disease attending the Sickle Cell Clinic of the University Hospital of the West Indies… CONTINUE READING

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Neurologic manifestations associated with parvovirus B19 infection.

  • Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
  • 2009
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