Cerebrovascular amyloidosis in squirrel monkeys and rhesus monkeys: apolipoprotein E genotype.

@article{Morelli1996CerebrovascularAI,
  title={Cerebrovascular amyloidosis in squirrel monkeys and rhesus monkeys: apolipoprotein E genotype.},
  author={Laura Morelli and Lin Wei and Ant{\'o}nio Amorim and Jill C McDermid and Christian R. Abee and Blas Frangione and Linda C Walker and {\'E}mile L{\'e}vy},
  journal={FEBS letters},
  year={1996},
  volume={379 2},
  pages={132-4}
}
Some neuropathological changes characteristic of aging and Alzheimer's disease (AD) in humans are present also in senescent non-human primates. The human apoE4 allele is associated with an increased risk of developing late-onset familial and sporadic AD. We found that rhesus monkeys and three subspecies of squirrel monkeys are homozygous for apoE phenotype… CONTINUE READING