Cerebrovascular Pathology and Dementia in Autopsied Honolulu‐Asia Aging Study Participants

  title={Cerebrovascular Pathology and Dementia in Autopsied Honolulu‐Asia Aging Study Participants},
  author={L. White and H. Petrovitch and J. Hardman and J. Nelson and D. Davis and G. Ross and K. Masaki and L. Launer and W. Markesbery},
  journal={Annals of the New York Academy of Sciences},
  • L. White, H. Petrovitch, +6 authors W. Markesbery
  • Published 2002
  • Medicine
  • Annals of the New York Academy of Sciences
  • Abstract: Clinicopathologic data from 285 autopsies were analyzed. The decedents were long‐standing participants in the Honolulu‐Asia Aging Study, a prospective epidemiologic investigation of stroke, neurodegenerative diseases, and aging. We assessed the prevalence at death of four primary neuropathologic processes using specific microscopic lesions as indicators. An algorithm was developed to assign each decedent to one of six subsets, corresponding to pathologic dominance by microvascular… CONTINUE READING
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