Cerebrospinal fluid markers of idiopathic intracranial hypertension: is the renin-angiotensinogen system involved?

@article{Brettschneider2011CerebrospinalFM,
  title={Cerebrospinal fluid markers of idiopathic intracranial hypertension: is the renin-angiotensinogen system involved?},
  author={Johannes Brettschneider and Nele Hartmann and Vera Lehmensiek and Helga Mogel and Albert Christian Ludolph and Hayrettin Tumani},
  journal={Cephalalgia : an international journal of headache},
  year={2011},
  volume={31 1},
  pages={116-21}
}
BACKGROUND The causes underlying idiopathic intracranial hypertension (IIH) are poorly understood. METHODS To identify disease-related biomarkers that could offer a new insight into IIH pathology, we analyzed the cerebrospinal fluid (CSF) of 18 patients with IIH and 18 controls using two-dimensional fluorescence differential in-gel electrophoresis (2-D DIGE). RESULTS We found six proteins that were upregulated in IIH (sterol regulatory element-binding protein 1, zinc-alpha-2-glycoprotein… CONTINUE READING
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