Cerebrospinal fluid macrophage biomarkers in amyotrophic lateral sclerosis

@article{Thompson2018CerebrospinalFM,
  title={Cerebrospinal fluid macrophage biomarkers in amyotrophic lateral sclerosis},
  author={Alexander G Thompson and Elizabeth T. Gray and Marie-La{\"e}titia Th{\'e}z{\'e}nas and Philip D. Charles and Samuel G. Evetts and Michele T Hu and Kevin Talbot and Roman Fischer and Benedikt M. Kessler and Martin R. Turner},
  journal={Annals of Neurology},
  year={2018},
  volume={83},
  pages={258–268}
}
OBJECTIVE The neurodegenerative disease, amyotrophic lateral sclerosis (ALS), is a heterogeneous clinical syndrome involving multiple molecular pathways. The development of biomarkers for use in therapeutic trials is a priority. We sought to use a high-throughput proteomic method to identify novel biomarkers in individual cerebrospinal fluid (CSF) samples. METHODS Liquid chromatography/tandem mass spectrometry with label-free quantification was used to identify CSF proteins using samples from… CONTINUE READING
5
Twitter Mentions

Citations

Publications citing this paper.
SHOWING 1-10 OF 14 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 28 REFERENCES

A language and environment for statistical computing

  • R R Core Team
  • ed. Vienna, Austria: R Foundation for Statistical Computing;
  • 2015
VIEW 1 EXCERPT