Cerebrospinal fluid levels of oxytocin in Prader-Willi syndrome: a preliminary report.

@article{Martn1998CerebrospinalFL,
  title={Cerebrospinal fluid levels of oxytocin in Prader-Willi syndrome: a preliminary report.},
  author={Andr{\'e}s Barriga Mart{\'i}n and Matthew State and George M. Anderson and Walter Kaye and Jeanne M. Hanchett and Claire W McConaha and William G. North and James F. Leckman},
  journal={Biological psychiatry},
  year={1998},
  volume={44 12},
  pages={1349-52}
}
BACKGROUND Prader-Willi syndrome (PWS) is a genetic disorder characterized by mental retardation, appetite dysregulation, and a high risk for obsessive-compulsive disorder (OCD). Microscopic abnormalities of the hypothalamus have been described in PWS, and oxytocin has been implicated in both appetite regulation and OCD. METHODS Oxytocin and arginine vasopressin (AVP) were measured in the cerebrospinal fluid of 5 subjects with PWS (2 male, 3 female) and in 6 normal control subjects (all… CONTINUE READING
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