Cerebrospinal fluid levels of Alzheimer’s disease biomarkers in middle-aged patients with type 1 diabetes

@article{Ouwens2014CerebrospinalFL,
  title={Cerebrospinal fluid levels of Alzheimer’s disease biomarkers in middle-aged patients with type 1 diabetes},
  author={D Margriet Ouwens and Eelco van Duinkerken and S. Niki M. Schoonenboom and Daniella Herzfeld de Wiza and Martin Klein and Larissa W. van Golen and Petra J. W. Pouwels and Frederik Barkhof and Annette C Moll and Frank Jan Snoek and Charlotte E Teunissen and Philip Scheltens and Michaela Diamant},
  journal={Diabetologia},
  year={2014},
  volume={57},
  pages={2208-2214}
}
Type 1 diabetes is associated with moderate cognitive decline and cerebral alterations and may lead to an increased risk of dementia, including Alzheimer’s disease. This study aimed to investigate the levels of risk markers for Alzheimer’s disease in middle-aged patients with type 1 diabetes and controls, and their potential associations with cognitive and cerebral measures. Levels of β-amyloid (Aβ) 42, Tau, phosphorylated Tau (pTau), the soluble form of low-density lipoprotein receptor-related… CONTINUE READING
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