Cerebrospinal fluid cytokine levels and cognitive impairment in cerebral malaria.

  title={Cerebrospinal fluid cytokine levels and cognitive impairment in cerebral malaria.},
  author={Chandy C John and Angela Panoskaltsis-Mortari and Robert O Opoka and Gregory S. Park and P J Orchard and Anne M. Jurek and Richard I. Idro and Justus S Byarugaba and Michael J Boivin},
  journal={The American journal of tropical medicine and hygiene},
  volume={78 2},
Cerebrospinal fluid (CSF) and serum levels of 12 cytokines or chemokines important in central nervous system (CNS) infections were measured in 76 Ugandan children with cerebral malaria (CM) and 8 control children. As compared with control children, children with cerebral malaria had higher cerebrospinal fluid levels of interleukin (IL)-6, CXCL-8/IL-8, granulocyte-colony stimulating factor (G-CSF), tumor necrosis factor-alpha (TNF-alpha), and IL-1 receptor antagonist. There was no correlation… CONTINUE READING


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