Cerebrospinal fluid concentrations of somatostatin and biogenic amines in grown primates reared by mothers exposed to manipulated foraging conditions.

@article{Coplan1998CerebrospinalFC,
  title={Cerebrospinal fluid concentrations of somatostatin and biogenic amines in grown primates reared by mothers exposed to manipulated foraging conditions.},
  author={Jeremy D. Coplan and Ronald C Trost and Michael J. Owens and Thomas B. Cooper and J. M. Gorman and Charles B. Nemeroff and Leonard A. Rosenblum},
  journal={Archives of general psychiatry},
  year={1998},
  volume={55 5},
  pages={473-7}
}
BACKGROUND In an earlier study, infant primates were nursed by mothers randomly assigned to variable foraging demand (VFD) or nonvariable foraging conditions (non-VFD). A group of grown VFD-reared subjects demonstrated elevations of cisternal cerebrospinal fluid (CSF) corticotropin-releasing factor concentrations and decreased CSF cortisol levels vs non-VFD counterparts. To further characterize neurobiological sequelae of disturbed early rearing, CSF concentrations of serotonin, dopamine, and… CONTINUE READING
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