Cerebrospinal fluid biomarkers for Parkinson's disease - a systematic review.

  title={Cerebrospinal fluid biomarkers for Parkinson's disease - a systematic review.},
  author={Andreas Dammann Andersen and Michael Binzer and Egon Stenager and Jan Bert Gramsbergen},
  journal={Acta neurologica Scandinavica},
  volume={135 1},
Diagnosis of Parkinson's disease (PD) relies on clinical history and physical examination, but misdiagnosis is common in early stages. Identification of biomarkers for PD may allow early and more precise diagnosis and monitoring of dopamine replacement strategies and disease modifying treatments. Developments in analytical chemistry allow the detection of large numbers of molecules in plasma or cerebrospinal fluid, associated with the pathophysiology or pathogenesis of PD. This systematic… CONTINUE READING
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