Cerebrospinal fluid Tau/α-synuclein ratio in Parkinson's disease and degenerative dementias.


Although alpha-synuclein is the main constituent of Lewy bodies, cerebrospinal fluid determination on its own does not seem fundamental for the diagnosis of synucleinopathies. We evaluated whether the combination of classical biomarkers, Aβ(1-42) , total tau, phosphorylated tau, and α-synuclein can improve discrimination of Parkinson's disease, dementia… (More)
DOI: 10.1002/mds.23670