Cerebrospinal fluid CXCL13 in multiple sclerosis: a suggestive prognostic marker for the disease course.

@article{Khademi2011CerebrospinalFC,
  title={Cerebrospinal fluid CXCL13 in multiple sclerosis: a suggestive prognostic marker for the disease course.},
  author={Mohsen Khademi and Ingrid Kockum and Magnus L. Andersson and Ellen Iacobaeus and Lou Brundin and Finn Thorup Sellebjerg and Jan Hillert and Fredrik Piehl and Tomas Olsson},
  journal={Multiple sclerosis},
  year={2011},
  volume={17 3},
  pages={335-43}
}
BACKGROUND Levels of CXCL13, a potent B-cell chemoattractant, are elevated in the cerebrospinal fluid (CSF) during multiple sclerosis (MS) and are associated with markers of MS activity. Levels decrease upon effective treatments. OBJECTIVE Here we validate the potential role of CSF CXCL13 as a biomarker for aspects of MS in a large amount of clinical material, the majority collected at early diagnostic work-up. METHODS CXCL13 was measured by ELISA in 837 subjects: relapsing-remitting MS… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 7 times. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 63 extracted citations

Intrathecal oligoclonal IgG synthesis in multiple sclerosis

Journal of Neuroimmunology • 2013
View 4 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…