Cerebrospinal fluid, plasma, and saliva in the BioFIND study: Relationships among biomarkers and Parkinson's disease Features

@inproceedings{Goldman2018CerebrospinalFP,
  title={Cerebrospinal fluid, plasma, and saliva in the BioFIND study: Relationships among biomarkers and Parkinson's disease Features},
  author={Jennifer G Goldman and Howard F. Andrews and Amy Amara and Anna Naito and Roy N Alcalay and Leslie M. Shaw and Peggy Taylor and Tao Xie and Paul J. Tuite and Claire Henchcliffe and Penelope Hogarth and Samuel A. Frank and Marie-H{\'e}l{\`e}ne Saint-Hilaire and Mark Frasier and Vanessa Arnedo and Alyssa Reimer and Margaret Sutherland and Christine Swanson-Fischer and Katrina Gwinn and Un Jung Kang},
  booktitle={Movement disorders : official journal of the Movement Disorder Society},
  year={2018}
}
OBJECTIVE Examine relationships among neurodegenerative biomarkers and PD motor and nonmotor symptoms. BACKGROUND CSF alpha-synuclein is decreased in PD versus healthy controls, but whether plasma and saliva alpha-synuclein differentiate these groups is controversial. Correlations of alpha-synuclein among biofluids (CSF, plasma, saliva) or biomarkers (eg, beta-amyloid, tau [total, phosphorylated]) are not fully understood. The relationships of these biomarkers with PD clinical features remain… CONTINUE READING
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